The Translational Challenge in Medicine at the Nanoscale 1
نویسندگان
چکیده
www.panstanford.com Raj Bawa, MS, PhD,a S. R. Bawa, MSc, PhD,b and Ratnesh N. Mehra, DOc aBawa Biotech LLC, Ashburn, Virgina, USA and Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA bBawa Biotech LLC, Schenectady, New York, USA cDepartment of Neurosurgery, Michigan State University College of Osteopathic Medicine, St. John Providence Health System, Michigan, USA
منابع مشابه
Nanoscale Studies on Aggregation Phenomena in Nanofluids
Understanding the microscopic dispersion and aggregation of nanoparticles at nanoscale media has become an important challenge during the last decades. Nanoscale modeling techniques are the important tools to tackle many of the complex problems faced by engineers and scientists. Making progress in the investigations at nanoscale whether experimentally or computationally has helped understand th...
متن کاملO 7: KCNK2 Regulates the Nanoscale Formation of Immune Docking Structures on Brain Endothelial Cells Under Autoinflammatory Conditions
KCNK2 was previously shown to regulate immune-cell trafficking into the central nervous system (CNS). Kcnk2-/- mice demonstrated a more severe disease course in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, due to an increased immune-cell migration into the CNS. An upregulation of the cellular adhesion molecules ICAM1 and VCAM1 on brain endothelial cells in K...
متن کاملProtective Role of Hypothermia Against Heat Stress in Differentiated and Undifferentiated Human Neural Precursor Cells: A Differential Approach for the Treatment of Traumatic Brain Injury
Introduction: The present study aimed to explore protective mechanisms of hypothermia against mild cold and heat stress on highly proliferative homogeneous human Neural Precursor Cells (NPCs) derived from Subventricular Zone (SVZ) of human fetal brain. Methods: CD133+ve enriched undifferentiated and differentiated human NPCs were exposed to heat stress at 42°C. Then, Western-blot qua...
متن کاملEffect of Nanoscale Titanium Dioxide Particles on the Germination and Growth of Canola (Brassica napus)
An investigation was initiated to examine the effects of nanoscale titanium dioxide particles on plant growth and development. In view of the widespread cultivation of canola in Iran and in other parts of the globe and in view of the potential influence of titanium on its growth, this plant was chosen as the model system. Canola seeds were separately treated with different concentrations of nan...
متن کاملTranslational Antidote Research: A Bedside to Bench Tale
Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. Interest in the development of fomepizole was spurred in the 1960s. Shortly t...
متن کامل